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cAMP-dependent protein kinase (PKA) is ubiquitous in every single mammalian cell Along with the PKA signaling network regulating processes as assorted as memory, differentiation, enhancement, the mobile cycle, and circadian rhythms. Considered one of our plans, Together with elucidating constructions on the PKA subunits, is usually to map the PKA p

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Metabolism touches nearly all areas of biology, and defects during the regulation of biochemical reactions normally contribute to disease pathogenesis. Inside the context of most cancers, tumors need to reprogram these networks to gasoline their aggressive development and endure. The complexity and interconnected nature of metabolic pathways necess

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